Search on: HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT 
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Descriptor English:   Hypoxia-Inducible Factor 1, alpha Subunit 
Descriptor Spanish:   Subunidad alfa del Factor 1 Inducible por Hipoxia 
Descriptor Portuguese:   Subunidade alfa do Fator 1 Induzível por Hipóxia 
Tree Number:   D12.776.260.103.625.750
D12.776.930.125.625.750
Definition English:   Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN. 
History Note English:   2006(2001) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50949 
Unique Identifier:   D051795 

Occurrence in VHL:
 

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